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Location: Virus Disease > Ecthyma- Contagious -ORF

Ecthyma- Contagious -ORF



Orf is an infectious disease of sheep and goats affecting primarily the lips of young animals. The disease also goes by the names "Contagious Ecthyma, Contagious pustular dermatitis, and Sore-Mouth".



Orf is an infectious disease of sheep and goats affecting primarily the lips of young animals. The disease also goes by the names "Contagious Ecthyma, Contagious pustular dermatitis, and Sore-Mouth". The virus may occasionally infect humans and is considered a zoonosis. Orf is caused by a poxvirus (genus Parapoxvirus). The virus is highly resistant to drying and may remain infectious in dried scabs for up to 12 years. Animals become infected by direct contact with lesions or mucous membranes of infected animals, or by the transfer of virus by contaminated equipment used on the animals. The disease starts as papules or vesicles (small bumps and blisters) on the skin of the lips, nostrils eyelids, and ears. It may also affect the udder (nursing ewes) or the feet. Eventually the papules and vesicles break open and scab; these are often very sore and may be numerous. As the sores heal the granulation tissue will proliferate and produce masses with a "cauliflower" appearance. The course of the disease is 1-4 weeks with a 2-3 day incubation. Humans become infected with the virus by direct contact with infected sheep or equipment contaminated with body fluids. The disease in humans is usually characterized by a single papular or pustular lesion (small bump/swelling) where the virus enters the skin (e.g. on the hand). The papule usually becomes painful and gradually becomes a firm weeping nodule. Regional lymph nodes may also become swollen. Usually the course of the disease lasts 2-4 weeks following a 3-7 day incubation. More widespread disease may occur as well as severe ocular lesions.

All persons working with infected sheep (the cage or room will be marked) should protect their hands by wearing gloves and washing hands as soon as possible after exposure. All equipment used on sheep should be washed and decontaminated. It should be remembered that gates and pens also may harbor the virus - gloves should be worn at all times working in the animal rooms.
 

Orf is a virus infection of the skin contracted from sheep and goats.

Orf is caused by a virus called the parapox virus, which infects mainly young lambs and goats who contract the infection from one another or possibly from persistence of the virus in the pastures. Human lesions are caused by direct inoculation of infected material.

Who is affected?

Orf is not uncommon among sheep farmers, shearers, freezing workers, vets and farmersī wives or their children who bottle-feed lambs. Children may also acquire it from playing on infected pasture. Butchers, meat porters and housewives are sometimes infected from carcasses, especially sheep heads. A similar condition, caused by a related virus, occurs in dairy farmers and is called Milkers' Nodule.

What are the appearances?

After an incubation period of 5 or 6 days a small, firm, red or reddish-blue lump enlarges to form a flat-topped, blood-tinged pustule or blister. The fully developed lesion is usually 2 or 3 cm in diameter but may be as large as 5 cm. Characteristically, although there appears to be pus under the white skin, incising this will reveal firm, red tissue underneath. The orf lesion is sometimes irritable during the early stages and is often tender. Orf lesions are generally solitary or few in number. They occur most commonly on the fingers, hands or forearms but can appear on the face. Red streaks up the lymph channels with enlargement of the lymph glands on the inner side of the elbow and/or under the arm are not uncommon. There may be a mild fever.

Orf
Typical orf arising on the hand of a sheep farmer

Patients, whose immunity is reduced for some reason, may develop larger or unusual orf lesions. Rarely widespread small blisters may occur, suggesting blood stream spread of the orf virus, but resolve after a few weeks.

A secondary allergy rash to the presence of the orf virus, erythema multiforme, occasionally develops, typically 10-14 days after the onset of orf, to give small blistery red ring-like lesions on the arms and legs. Less distinctive red rashes, 'toxic erythemas' also occur and rarely the blistering disorder pemphigoid.

Orf recovers spontaneously in 3 to 6 weeks.

Treatment of Orf

No specific treatment is necessary in most cases. The lesion may be covered to prevent contaminating the environment or other people, although person-to person spread is very uncommon. Any secondary bacterial infection should be treated. Large lesions can be removed by shave excision.




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